Baked Grapefruit Recipes Cut a grapefruit in half. Use a knife to separate the grapefruit into sections (pull away from the wall) drizzle each half with honey. Bake at 350 degrees for 12 to 15 minutes. A great way to enjoy grapefruit! Submit a Comment Cancel replyYour email address will not be published. Required fields are marked *Comment Name * Email * Website This site uses Akismet to reduce spam. Learn how your comment data is processed.